How to Choose an MK-7 Oil Concentration

Amber laboratory vials illustrating Vitamin K2 MK-7 oil concentration selection
Conceptual concentration-selection image; confirm the applicable current specification for the exact commercial grade.

Compare verified 1,500 and 4,500 ppm grades first; treat 1% and 5% oils as project options requiring an applicable current specification.

Key takeaways

  • Start with a mass-balance calculation and minimum reliable weighing quantity.
  • Higher potency reduces carrier load but magnifies weighing and dispersion risk.
  • Ureda’s supplied TDS documents verify 1,500 and 4,500 ppm MCT-oil grades; request the current applicable TDS for other concentrations.

Verified and project-specific concentrations

1,500 ppm
0.15% · 1.5 mg/g
Verified supplied TDS
4,500 ppm
0.45% · 4.5 mg/g
Verified supplied TDS
10,000 ppm
1% · 10 mg/g
Confirm current TDS
50,000 ppm
5% · 50 mg/g
Confirm current TDS

A transparent calculation method

Preparation required (g) = total MK-7 required in batch (mg) ÷ concentration (mg/g)

If a batch requires 1,000 mg of MK-7, the theoretical preparation requirement is about 666.7 g at 1,500 ppm or 222.2 g at 4,500 ppm. Manufacturing overage must be justified by process and stability data rather than assumed.

Label Equivalent MK-7 per gram Document status
1,500 ppm 0.15% 1.5 mg Verified supplied TDS
4,500 ppm 0.45% 4.5 mg Verified supplied TDS
10,000 ppm 1% 10 mg Project option; document required
50,000 ppm 5% 50 mg Project option; document required

Why higher is not automatically better

  • Smaller ingredient mass magnifies weighing-error risk.
  • Distribution through the oil fill becomes more critical.
  • Higher-potency handling may need tighter operating controls.
  • Lower carrier load can benefit space-constrained formulas.

Carrier and market considerations

For MCT projects, coconut-derived and palm-derived sources may be discussed. Confirm carrier origin, allergen positioning and destination-market documentation before order confirmation. Commercial preference varies by customer and should not be confused with a regulatory requirement.

What to include in your supplier brief

Provide the dose per serving, batch size, fill weight, smallest reliable weighing mass, preferred MCT source and destination market.

Need a concentration calculation?

Send Ureda your target dose, batch size and fill weight. We will calculate a practical starting range and confirm which current documents apply.

Request a quotation

Related guides: MK-7 oil vs powder · Cis vs trans MK-7

Technical note: Calculations are theoretical starting points. Confirm the current applicable TDS, COA, formulation process and finished-product stability before commercialization.

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If you have any questions, feel free to contact us at sales@uredapharm.com