Cis vs Trans MK-7: What Ingredient Buyers Should Check

Conceptual analytical visualization of extended and bent Vitamin K2 MK-7 configurations
Conceptual isomer-quality image; numerical criteria must be verified against the applicable current TDS and batch COA.

“All-trans” is useful positioning, but qualification still requires a numerical specification, analytical method and representative batch result.

Key takeaways

  • Assay and isomer profile describe different quality attributes.
  • The supplied Ureda T-1500 and T-4500 TDS documents set cis-MK-7 at no more than 2%.
  • Do not convert a numerical cis limit into an unsupported “100% all-trans” claim.

MK-7 can exist in different geometric configurations. The naturally relevant configuration is commonly described as all-trans. Cis isomers are monitored because configuration can affect biological-activity interpretation and ingredient quality.

Three quality terms that should not be confused

Term What it describes Buyer question
MK-7 assay Amount of menaquinone-7 active or preparation What is the range and method?
Cis-MK-7 Specified geometric-isomer content What is the maximum limit?
All-trans claim Configuration positioning What numerical data support the wording?

What Ureda’s supplied oil TDS states

Cis-MK-7
≤2%
MK-6
≤10%
of labelled MK-7 amount

These criteria belong to the supplied T-1500 and T-4500 documents and should remain linked to those exact grades and document revisions.

Why assay alone is not the whole story

Two preparations with the same declared assay can differ in isomer profile, related menaquinones, contaminants, carrier and stability. Professional qualification therefore reviews the complete specification and a representative batch COA—not a headline purity figure alone.

Supplier qualification checklist

  • Current TDS revision and exact grade name
  • Identity and assay methods
  • Cis-MK-7 acceptance criterion
  • Related menaquinone limits
  • Batch COA and traceability
  • Stability conditions and packaging
  • Market-specific regulatory documents

Comparing MK-7 suppliers or COAs?

Send Ureda the target grade, market and specification questions. We can provide the current applicable technical documents for evaluation.

Request technical documents

Related guides: MK-7 oil vs powder · Choosing MK-7 oil concentration

Technical note: This guide is for ingredient qualification and formulation planning. Verify every grade-specific value against the current applicable TDS and batch COA.

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